Perpustakaan Universitas Padjajaran
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Use of Subantimicrobial Dose Doxycycline as Adjunct Therapy in Periodontitis Patients (Rapid Review)

Introduction: Periodontitis is an inflammatory disease of periodontal tissue
due to pathogenic microorganisms interacting with host responds. ...

  • CodeCallNoLokasiKetersediaan
    Per1 - 189189 617.63 Aud UJatinangor (Periodonsia)Tersedia namun tidak untuk dipinjamkan - No Loan
  • Perpustakaan
    Fakultas Kedokteran Gigi
    Judul Seri
    -
    No. Panggil
    617.63 Aud U
    Penerbit FKG Unpad : FKG UNPAD JATINANGOR.,
    Deskripsi Fisik
    -
    Bahasa
    English
    ISBN/ISSN
    160110180081
    Klasifikasi
    617.63
    Tipe Isi
    -
    Tipe Media
    -
    Tipe Pembawa
    -
    Edisi
    -
    Subyek
    periodontitis
    doxycycline
    host modulation
    Info Detil Spesifik
    -
    Pernyataan Tanggungjawab
  • Introduction: Periodontitis is an inflammatory disease of periodontal tissue
    due to pathogenic microorganisms interacting with host responds. Treatment
    scaling and root planing have been established as the standard in treating
    periodontitis, but there are limitations. The combination of additional therapy using
    Subantimicrobial Dose Doxycycline (SDD) is needed to overcome the excessive
    host response so that it can produce better therapeutic results. This study aims to
    determine the development of science regarding using SDD as an adjunct therapy
    in periodontitis patients. Methods: Rapid review method with literature screening
    and selection using the PRISMA protocol. The search strategy was carried out on
    the PubMed, Science Direct, and ProQuest databases using keywords and Boolean
    operators according to predetermined inclusion and exclusion criteria. Results:
    Five articles reviewed showed various changes in clinical parameters and
    inflammatory mediators. Changes in parameters that are considered significant
    and insignificant but still offer a better direction. Conclusion: The whole article
    shows that SDD positively affects the periodontal tissue, as seen by the decrease in
    Probing Depth (PD), Clinical Attachment Level (CAL), Bleeding on Probing
    (BOP), Gingival Index (GI), Plaque Index (PI), Matrix Metalloproteinase (MMP)
    and Gingival Ctevicular Fluid (GCF) which play a significant role in periodontitis.
    Keywords: doxycycline, host modulation, periodontitis

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