Perpustakaan Universitas Padjajaran
Pencarian Spesifik

Detail Cantuman

No image available for this title

Text  

4692- Characterization of Piperine-Bovine Serum Albumin and Piperine-Catfish Serum Albumin Nanoparticles (Nadia Khairunisa Mouna; Dr. Eri Amalia, MHSc; Dr. Dian Ayu Eka Pitaloka, M.Si; Dr. Erwahyuni Endang Prabandari, M.Si)

Piperine is the principal alkaloid compound derived from Piper nigrum, known for its various pharmacological activities, including antioxidant, ...

  • CodeCallNoLokasiKetersediaan
    FFUP202501884692Tersedia
  • Perpustakaan
    Fakultas Farmasi
    Judul Seri
    -
    No. Panggil
    4692
    Penerbit Fakultas Farmasi Universitas Padjadjaran : Jatinangor.,
    Deskripsi Fisik
    -
    Bahasa
    English
    ISBN/ISSN
    -
    Klasifikasi
    4692
    Tipe Isi
    -
    Tipe Media
    -
    Tipe Pembawa
    -
    Edisi
    -
    Subyek
    -
    Info Detil Spesifik
    -
    Pernyataan Tanggungjawab
  • Piperine is the principal alkaloid compound derived from Piper nigrum, known for its various pharmacological activities, including antioxidant, anti-inflammatory, and anticancer effects. However, the oral use of piperine faces limitations due to its poor water solubility and low absorption in the body, which reduces its therapeutic effectiveness. To address this issue, a nanotechnology-based approach is employed to enhance the solubility and bioabsorption of piperine. In this study, piperine was formulated into nanoparticles using the desolvation method with albumin carriers derived from both Bovine Serum Albumin (BSA) and Catfish Serum Albumin (CSA). Albumin was selected due to its ability to improve the solubility of hydrophobic compounds and its role as a biocompatible and biodegradable drug delivery system. Catfish-derived albumin (CSA) also presents a promising local alternative that is more economical and sustainable. The characterization results showed that the nanoparticle system successfully increased the solubility of piperine and produced nano-sized particles suitable for enhancing bioabsorption. Therefore, this piperine-albumin nanoparticle formulation may serve as an effective strategy to optimize the therapeutic potential of piperine by improving its solubility and bioavailability.
    Keywords: Piperine, Nanoparticles, Albumin, Bioabsorption

  • Tidak tersedia versi lain

  • Silakan login dahulu untuk melihat atau memberi komentar.


//

Informasi